New guidelines have recently been published by the European Society of Cardiology on the management of patients with atrial fibrillation. They are summarised in the article New European Guidelines on Atrial Fibrillation BMJ 2011;342:d897. Two of the most important recommendations are the increased identification of patients at risk of stroke, and wider use of anticoagulants. The original CHADS2 score has now been replaced with the CHA2DS2-VASc system. Patients with each of the following demographics score a point (congestive heart failure, hypertension, diabetes, vascular disease, age >65 and female). Patients with each of the following score an additional 2 points: previous stroke or TIA, age >75. For a patient with a score of zero, no anticoagulant is required. For those with a score of 1 or greater, oral anticoagulants are recommended over aspirin 75mg. Although aspirin is still considered a reasonable option for patients with a risk score of zero to one following initial assessment, it is no longer the preferred option for most patients.
The new guidelines have been created following a wave of evidence of the benefits of oral anticoagulants over aspirin and new evidence has been released which shows that patients on warfarin or aspirin have a similar risk of bleeding. In addition, new oral anticoagulants are beginning to emerge which may replace warfarin in the future because they don't require therapeutic monitoring of levels. Dabigatran is a direct thrombin inhibitor that does not require therapeutic monitoring. Patients who are on warfarin presently and stable on the drug should not be changed to dabigatran but pending approval of the direct thrombin inhibitor, it may replace warfarin in the forthcoming years.
National Patient Safety Agency: NG Tube Placement
On a separate note but carrying on with the national patient safety agency theme, an article appeared in the BMJ this week on the topic of Checking placement of NG feeding tubes in adults. BMJ 2011;342:d2586. NG feeding tubes are frequently used for patients who develop dysphagia or those on ventilators in intensive care for short to medium term use as an alternative to longer term feeding via a PEG tube. Most NG tubes are inserted safely however there is potential for serious patient harm to occur should the tube become displaced from the stomach. Aspiration pneumonia following incorrect NG tube insertion can be potentially fatal. So how do we reduce the risk of this occurring? Testing acidity of stomach contents by using pH litmus paper is the gold standard first line check, with X-ray interpretation as second line. However, since 2005 in England there have been 21 reported deaths resulting from misplaced NG tubes with misinterpretation of xray images the leading contributary factor. This is a serious avoidable event, and in one audit, less than one third of junior doctors had received training on interpreting Xrays for misplaced tubes or were aware of existing guidelines. Ways to stop adverse events from occurring:
- Avoid placing NG tubes outside normal working hours wherever possible.
- Do not give NG tube feeding to patients at high risk of aspiration
- Do not place NG tubes without prior training including how to interpret the xrays
- Use the online website www.trainingngt.co.uk for guidance
- Do not flush the NG tube with anything until pH testing is completed
- pH level of between 1 and 5.5 is acceptable. No more.
- If no aspirate can be obtained or the pH level is >5.5, Xray request asking specifically for interpretation of NG tube placement. Ask a radiologist for interpretation advice if unsure.
- After radiography, clearly document decision and next steps for the patient eg. safe to use.
- Tubes should be checked once daily for correct placement and before giving feed or medication because they may have become displaced.